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 Posté le: Mer Sep 25, 2013 10:25 am Sujet du message: Obesity increases risk of death from flu three-fol |
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{Obesity increases risk of death from flu three-fold, new study shows}
Obese people face nearly three-fold higher odds of dying from a flu infection and should be given priority access to flu shots, according to the authors of a new study challenging well-accepted assumptions about who is most at risk of death from influenza.The global study by researchers at Hamilton’s McMaster University suggests obesity should be considered a new and dangerous risk factor for serious complications from flu.Canada’s National Advisory Committee on Immunization recommends the “morbidly obese” — those with a body mass index, or BMI, of 40 or higher — be among the priority groups for flu shots.But the new study found that the risk of dying increases at a BMI of 30 or greater. “We believe that 30 is probably the better cutoff than 40,[url=http://learn.webbizcreators.com/activity/p/95407/]福島第一の汚染水、２３億ベクレル検出 東電が調査[/url],” said lead author Dr. Dominik Mertz, assistant professor of medicine at McMaster’s Michael G. DeGroote School of Medicine.In Canada, one in four adults and one in 10 children — six million Canadians — are obese, according to the Canadian Obesity Network.Mertz said that it’s not clear whether obesity itself increases the risk of death from influenza or the “co-morbid” or co-existing conditions such as diabetes that tend to go along with it.The study, funded by the World Health Organization, is published online in the British Medical Journal.“Policy makers around the globe make recommendations for priority vaccination for patients in certain high risk groups,” Mertz said. “However, nobody really looked at the evidence in much detail, and the so-called traditional risk factors were just taken over, year from year, and not really critically reviewed.”In all, the researchers analyzed 239 studies published between 1918 and 2011 involving more than 610,[url=http://www.moncler-jacket.net]moncler on sale[/url],000 people. The vast majority of studies of pandemic flu involved the H1N1 outbreak in 2009. Most of the studies on seasonal flu were conducted over the last 10 to 20 years.The researchers looked at risk factors for severe complications of influenza, including pneumonia,[url=http://www.moncler-jacket.net]moncler on sale[/url], admission to a hospital or intensive care unit, the need for artificial ventilation and death.Overall, the evidence supporting risk factors for severe flu complications ranged from “limited to absent,[url=http://www.moncler-jacket.net]womens moncler down coat[/url],[url=http://www.moncler-jacket.net]moncler down jackets[/url],” the researchers report.Canada’s advisory panel on immunization recommends that elderly people,[url=http://www.moncler-jacket.net]moncler outlet[/url], children aged six to 59 months and pregnant women be among those groups placed at the front of the queue for flu shots.The McMaster study found that elderly people had the highest risk of death during both seasonal and pandemic flu seasons.Children under five had a higher risk of pneumonia. However,[url=http://www.moncler-jacket.net]moncler down jackets[/url], they had a lower risk of death and hospital admission than older children. The authors said they could not find convincing evidence “to prioritize vaccination of young children compared to adults.”Pregnancy increased the risk of admission to hospital but not for any of the other outcomes. However, women who contracted flu within the first four weeks of giving birth had a more than four-fold increased risk of death during pandemic influenza.The findings keep with the recommendation to prioritize flu shots for pregnant women because of the increased risk of death so soon after delivery, Mertz said. The risk of complications from flu also appears to increase in the third trimester of pregnancy.Overall,[url=http://www.moncler-jacket.net]discount moncler jackets[/url],[url=http://www.tattoochitchat.com/view/post:1862965]Coparmex recomienda reducir tamaño del Gobierno Fe[/url], the team found that obesity “is an important risk factor for death with both pandemic and seasonal influenza.” Mertz said the evidence implicating obesity was stronger than for many of the traditional risk factors.People with cardiovascular and neuromuscular diseases were also found to have more complications from flu, supporting that they be among the priority groups for vaccination and anti-viral therapy.However, American aboriginal people, another traditional risk group, were not found to have more complicated flu, according to the study. Nor were other ethnic minorities.“Health policy makers need to consider the minimal, or even lack of evidence supporting many of those traditional risk factors,” Mertz said. “If we can define the risk groups we can optimally allocate vaccines, and that is particularly important when and if there is a vaccine shortage, say during a new pandemic.”Huge lineups and frustration dominated the first week of the H1N1 vaccination campaign in the fall of 2009, the biggest immunization program in the nation’s history. Public flu clinics were shutdown early after federal officials initially received only one-fifth the amount of vaccine they had expected to distribute nationwide.An estimated three to five million cases of severe flu, and up to half a million flu-related deaths,[url=http://www.tagdeaf.com/index.php?do=/blog/add/]Make Toby Land ineligible for parole for 15 years[/url], are reported annually worldwide.Mertz said he wouldn’t expect a recommendation to vaccinate people with a BMI of 30 or greater to result in vaccine shortages during normal flu years. The annual flu shot is a notoriously tough sell. According to an Ipsos Reid poll in 2012, 36 per cent of Canadians reported they were vaccinated against the flu.However, in the case of a new pandemic and limited vaccine supply, “vaccination of all obese patients might not be feasible,” and health policy makers may need to consider limits, he said.skirkey@postmedia.comTwitter.com/sharon_kirkey
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